Which human genes are the most studied?

Top 100 human studied genes

Updated once every week using the NCBI Gene database by counting the number of abstracts associated with each gene.
Rank Gene symbol # Abstracts Disease
1TP538288Liver carcinoma
2TNF5258Rheumatoid Arthritis
3EGFR4560Adenocarcinoma
4VEGFA3985Neoplasm Metastasis
5APOE3939Alzheimer's Disease
6IL63863Depressive disorder
7TGFB13619Camurati-Engelmann Syndrome
8MTHFR3230Cerebrovascular accident
9ESR12819ESTROGEN RESISTANCE
10NFKB12710Adenocarcinoma
11AKT12709Meningioma
12IL102678Behcet Syndrome
13HLA-DRB12545Sarcoidosis
14HIF1A2529Heart failure
15BRCA12494Malignant neoplasm of breast
16MMP92450Neoplasm Metastasis
17IL1B2432Alzheimer's Disease
18ACE2404Allanson Pantzar McLeod syndrome
19ERBB22386Mammary Neoplasms
20APP2340Alzheimer's Disease
21CTNNB12140Medulloblastoma
22STAT32085Hyper-Ige Recurrent Infection Syndrome, Autosomal Dominant
23CDKN2A2066melanoma
24SLC6A42052Major Depressive Disorder
25GSTM12043Asthma
26ABCB12023Liver carcinoma
27PTGS22006Depressive disorder
28AR2003Androgen-Insensitivity Syndrome
29TLR41971Necrotizing Enterocolitis
30CD41942Muscular Dystrophy, Duchenne
31CXCL81939Inflammation
32HLA-B1913Behcet Syndrome
33ADIPOQ1903Obesity
34KRAS1898Juvenile Myelomonocytic Leukemia
35MAPK11850Neoplasm Metastasis
36NOS31836Myocardial Infarction
37CRP1835Rheumatoid Arthritis
38PPARG1833Obesity
39PTEN1800Hamartoma Syndrome, Multiple
40BRAF1787Cardio-facio-cutaneous syndrome
41BCL21711Lymphoma, Follicular
42IFNG1707Diabetes Mellitus, Insulin-Dependent
43GSTT11707Lung Neoplasms
44VDR1668Vitamin D-Dependent Rickets, Type 2A
45BDNF1667Depressive disorder
46CXCR41654WHIM syndrome
47CDH11643Hereditary Diffuse Gastric Cancer
48COMT1638Bipolar Disorder
49MDM21612Mammary Neoplasms
50MYC1592Burkitt Lymphoma
51IGF11565Insulin-Like Growth Factor I Deficiency
52MMP21551TORG-WINCHESTER SYNDROME
53MTOR1519SMITH-KINGSMORE SYNDROME
54BRCA21519FANCONI ANEMIA, COMPLEMENTATION GROUP D1
55CFTR1458Cystic Fibrosis
56CDKN1A1449Stomach Neoplasms
57CCR51441Hepatitis C
58GSTP11439Lung Neoplasms
59TERT1436Aplastic Anemia
60LEP1428Obesity
61HLA-DQB11415Narcolepsy
62HLA-A1410Stevens-Johnson Syndrome
63SNCA1389Lewy Body Disease
64MAPT1358Frontotemporal dementia
65CCND11341Malignant lymphoma, lymphocytic, intermediate differentiation, diffuse
66F21324Inherited Factor II deficiency
67JAK21311Polycythemia Vera
68MAPK31257Neoplasm Metastasis
69RELA1246Mammary Neoplasms
70F51240Factor V Deficiency
71CCL21239Coronary Artery Disease
72SERPINE11238Plasminogen Activator Inhibitor-1 Deficiency
73TLR21238Keratitis
74MAPK141210Schizophrenia
75SRC1205Mammary Neoplasms
76PIK3CA1145Liver carcinoma
77CXCL121125HIV Infections
78ITGB11113Neoplasm Metastasis
79FAS1109Autoimmune Lymphoproliferative Syndrome
80XRCC11098Stomach Neoplasms
81BIRC51086Liver carcinoma
82ATM1083Ataxia Telangiectasia
83ICAM11082Diabetic Retinopathy
84IL41074Asthma
85RB11073Retinoblastoma
86GSK3B1061Depressive disorder
87DRD21053Depressive disorder
88JUN1052Hypertensive disease
89CASP31041Status Epilepticus
90ITGB31033Thrombasthenia
91ESR21031Mammary Neoplasms
92PON11023Amyotrophic Lateral Sclerosis
93NOTCH11015Aortic Valve Disease 1
94EP3001009Rubinstein-Taybi Syndrome
95CYP1A11004Mammary Neoplasms
96AGT997Allanson Pantzar McLeod syndrome
97CD44989Neoplasm Metastasis
98CTLA4988Lymphoma, T-Cell, Cutaneous
99SP1984Schizophrenia
100SOD1978Amyotrophic Lateral Sclerosis

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